OpenAI · Agent Orchestration
AI Chemist (GPT-5.4)
OpenAI paired GPT-5.4 with Molecule.one's Maria agent to improve Chan-Lam coupling of primary sulfonamides, proposing TEMPO as an additive and running 10,080 wet-lab reactions; mean yield rose 16.6%→25.2%, >30%-yield reactions rose 15.6%→37.5%, with human bench repeats confirming gains for 11 of 14 substrate pairs. Targets a bottleneck for a pharmacophore in 91+ FDA-approved drugs.
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Published by Quanta AI Labs, an AI agency in India. Browse every week in AI News Weekly.