Google DeepMind · Cell-type DNA model

AlphaGenome 2

AlphaGenome 2 is a conditional DNA sequence model from Google DeepMind that predicts how DNA variants affect gene regulation in specific human cell types, rather than in broad tissue averages. On the TenK10K single-cell immune dataset it identified nearly twice as many causal variants as the original AlphaGenome fine-tuned on single-cell data (30% vs 16%). It is available now for non-commercial research via the AlphaGenome API and in private preview for commercial research.

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AlphaGenome 2

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